| Symbol | LOC111255642 |
| Name | TNFRSF10B 5' regulatory region |
| Type | biological-region |
| Source | mygene |
This record represents the 5' regulatory region of the TNF receptor superfamily member 10b (TNFRSF10B, also known as DR5) gene. It encompasses promoter elements located both upstream and downstream of the major start of transcription initiation. Tumor protein p53 and nuclear factor kappa B induce this promoter by binding to recognition elements located in a downstream intronic region. Bile acids, signaling through map kinase 8 (JNK), and apoptosis-causing factors activate this promoter thro
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