gene

CHRNB3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHRNB3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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0Experiments

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Summary

CHRNB3 (Cholinergic Receptor Nicotinic Beta Subunit 3) encodes a neuronal nicotinic acetylcholine receptor subunit implicated in Parkinson's disease, addiction, and cognitive function.

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🧬 Gene Info

Gene Symbol	CHRNB3
Full Name	Cholinergic Receptor Nicotinic Beta Subunit 3
Chromosome	8p11.21
Protein Type	Channel
Primary Expression	Brain (high), peripheral nervous system
Molecular Weight	50 kDa
Amino Acids	502 aa
Pathways	Mechanism
UniProt ID	P17787
NCBI Gene ID	1145
Ensembl ID	ENSG00000180988
OMIM	118505
GeneCards	CHRNB3
Human Protein Atlas	CHRNB3
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CHRNB3 — AlphaFold P17787 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CHRNB3 Gene

gene · 2904 words

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CHRNB3 Protein

protein · 771 words

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Pathway Diagram

graph TD
    CHRNB3["CHRNB3"]
    neurodegeneration["neurodegeneration"]
    CHRNB3 -->|"implicated_in"| neurodegeneration
    style CHRNB3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CHRNB3 in their description or question text

No additional research found