Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CLIP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
CLIP1 encodes a microtubule-binding protein that links endocytic vesicles to the cytoskeleton. Essential for intracellular transport, synaptic vesicle recycling, and neuronal function. Implicated in Alzheimer's and Parkinson's disease.
No AI portrait yet
| Gene Symbol | CLIP1 |
| Full Name | CLIP-Associating Protein 1 |
| Chromosome | 12q24.31 |
| Function | encodes a crucial microtubule-binding protein that functions as a molecular adaptor, linking endocytic vesicles and organelles to the microtubule cytoskeleton. |
| Primary Expression | Ubiquitous, high in neurons |
| Molecular Weight | 380 kDa |
| Amino Acids | 100 aa |
| UniProt ID | P30622 |
| NCBI Gene ID | 6249 |
| Ensembl ID | ENSG00000130779 |
| OMIM | 179838 |
| GeneCards | CLIP1 |
| Human Protein Atlas | CLIP1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CLIP1["CLIP1"]
neurodegeneration["neurodegeneration"]
CLIP1 -->|"implicated_in"| neurodegeneration
style CLIP1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CLIP1 in their description or question text
No additional research found