protein

CLRN1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLRN1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Clarin 1 is a small membrane protein with four transmembrane domains, similar to the tetraspanin superfamily.

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🔬 Protein Info

Gene Symbol	CLRN1PROTEIN
Protein Family	Clarin family, tetraspanin-like proteins
Function	is a protein encoded by the CLRN1 gene.
Subcellular Localization	to the plasma membrane and synaptic vesicles, playing essential roles in sensory
Molecular Weight	24 kDa
UniProt ID	Q9NYQ5
GeneCards	CLRN1PROTEIN
Human Protein Atlas	CLRN1PROTEIN
Retina	Photoreceptor cells (rods and cones)
Cochlea	Hair cells of the inner ear
Progressive hearing loss	Sensorineural hearing loss beginning in childhood
Retinitis pigmentosa	Progressive vision loss due to photoreceptor degeneration
Variable vestibular dysfunction	Balance problems in some patients
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CLRN1PROTEIN — AlphaFold Q9NYQ5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CLRN1 (Clarin 1)

protein · 608 words

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Pathway Diagram

graph TD
    CLRN1PROTEIN["CLRN1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CLRN1PROTEIN -->|"implicated_in"| neurodegeneration
    style CLRN1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CLRN1PROTEIN in their description or question text

No additional research found