Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COG5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | COG5 |
| Full Name | Conserved Oligomeric Golgi Complex 5 |
| Chromosome | 9q22.2 |
| Function | is a subunit of the COG complex, a hetero-octameric protein assembly critical for Golgi apparatus function. |
| Amino Acids | 755 aa |
| GeneCards | COG5 |
| Human Protein Atlas | COG5 |
| Retrograde trafficking | Recycling of trafficking machinery proteins |
| Glycosylation enzyme localization | Maintaining proper distribution of glycosyltransferases |
| Cargo transport | Ensuring efficient passage of proteins through the secretory pathway [3][4] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
COG5["COG5"]
neurodegeneration["neurodegeneration"]
COG5 -->|"implicated_in"| neurodegeneration
style COG5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity