gene

COG7

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about COG7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for COG7 — Conserved Oligomeric Golgi Complex 7

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🧬 Gene Info

Gene Symbol	COG7
Full Name	Conserved Oligomeric Golgi Complex 7
Chromosome	16p12.2
Function	is an essential subunit of the COG complex, functioning as part of lobe B to coordinate Golgi apparatus vesicular trafficking.
Subcellular Localization	of glycosyltransferases 2
Amino Acids	327 aa
GeneCards	COG7
Human Protein Atlas	COG7
Vesicle capture	Initial recognition and tethering of incoming vesicles
Fusion orchestration	Coordinating SNARE complex assembly
Cargo recognition	Ensuring proper selection of trafficking cargo [3][4]
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

COG7 — Conserved Oligomeric Golgi Complex 7

gene · 555 words

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Pathway Diagram

graph TD
    COG7["COG7"]
    neurodegeneration["neurodegeneration"]
    COG7 -->|"implicated_in"| neurodegeneration
    style COG7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning COG7 in their description or question text

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