Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COG8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | COG8 |
| Full Name | Conserved Oligomeric Golgi Complex 8 |
| Chromosome | 16q22.1 |
| Function | COG8 (approximately 611 amino acids) represents the C-terminal component of lobe B in the COG complex. It contains multiple coiled-coil domains that mediate interactions with other COG subunits, pa... |
| Subcellular Localization | of glycosyltransferases 3 |
| Amino Acids | 611 aa |
| GeneCards | COG8 |
| Human Protein Atlas | COG8 |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
COG8["COG8"]
neurodegeneration["neurodegeneration"]
COG8 -->|"implicated_in"| neurodegeneration
style COG8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||