protein

COQ4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COQ4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses
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Summary

Page for COQ4 Protein

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🔬 Protein Info
Gene SymbolCOQ4
Protein TypeEnzyme
FunctionThe COQ4 protein is essential for CoQ biosynthesis and functions as part of a multi-subunit complex in the inner mitochondrial membrane.
Molecular Weight36 kDa
UniProt IDQ9Y2R9
Ensembl IDENSG00000167862
GeneCardsCOQ4
Human Protein AtlasCOQ4
CoQ biosynthesisEssential for the final steps of ubiquinone synthesis
Mitochondrial electron transportEnables proper electron flow through Complexes I and II
Antioxidant protectionCoQ helps neutralize reactive oxygen species (ROS)
Membrane stabilizationMaintains mitochondrial membrane integrity
EncephalomyopathyProgressive muscle weakness and neurological deterioration
Hypertrophic cardiomyopathyHeart muscle thickening
Sensorineural hearing lossProgressive hearing impairment
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING
🔮 Predicted Structure: COQ4 — AlphaFold Q9Y2R9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

COQ4 Gene

gene · 570 words

COQ4 Protein

protein · 621 words

Pathway Diagram

graph TD
    COQ4["COQ4"]
    neurodegeneration["neurodegeneration"]
    COQ4 -->|"implicated_in"| neurodegeneration
    style COQ4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning COQ4 in their description or question text

No additional research found