Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COQ5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | COQ5 |
| Protein Type | Transferase |
| Function | COQ5 Gene (Coenzyme Q Biosynthesis Factor 5) provides instructions for making the COQ5 protein, a mitochondrial methyltransferase essential for coenzyme Q (CoQ10) biosynthesis |
| Primary Expression | various tissues: |
| Molecular Weight | 38 kDa |
| Amino Acids | 333 aa |
| Exons | 6 coding exons |
| UniProt ID | Q9NXK5 |
| Ensembl ID | ENSG00000108465 |
| GeneCards | COQ5 |
| Human Protein Atlas | COQ5 |
| Transcript length | ~1.2 kb coding sequence |
| Protein length | 333 amino acids |
| Molecular weight | ~38 kDa |
| Brain | Neurons throughout the cerebral cortex, hippocampus, cerebellum |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
COQ5["COQ5"]
neurodegeneration["neurodegeneration"]
COQ5 -->|"implicated_in"| neurodegeneration
style COQ5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COQ5 in their description or question text
No additional research found