gene

COQ7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COQ7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

1Analyses

1Outgoing

0Incoming

0Experiments

1Debates

Summary

Page for COQ7 Gene

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🧬 Gene Info

Gene Symbol	COQ7
Function	COQ7 Gene (Coenzyme Q Biosynthesis Factor 7) provides instructions for making the COQ7 protein, also known as coenzyme Q7 or mitochondrial coenzyme Q hydroxylase
Primary Expression	most tissues:
Molecular Weight	25 kDa
Amino Acids	248 aa
Exons	5 coding exons
UniProt ID	Q9UQB8
Ensembl ID	ENSG00000109113
GeneCards	COQ7
Human Protein Atlas	COQ7
Transcript length	~1.0 kb coding sequence
Protein length	248 amino acids
Molecular weight	~25 kDa
Brain	Throughout the CNS
Heart	High in cardiac muscle
Associated Diseases	neurodegeneration
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: COQ7 — AlphaFold Q9UQB8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

COQ7 Gene

gene · 639 words

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COQ7 Protein

protein · 877 words

→

Pathway Diagram

graph TD
    COQ7["COQ7"]
    neurodegeneration["neurodegeneration"]
    COQ7 -->|"implicated_in"| neurodegeneration
    style COQ7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

Target	Relation	Type	Str
CoQ10 biosynthesis	regulates	pathway	0.90

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

What molecular mechanisms cause iPLA2β deficiency to specifically damage mitocho

neurodegeneration | 2026-04-15 | 0 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The abstract shows that damaged mitochondrial inner membranes appear early in PL

closed · Rounds: 4 · Score: 0.95 · 2026-04-16

Related Research

Hypotheses and analyses mentioning COQ7 in their description or question text

No additional research found