gene

COQ9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COQ9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

1Analyses

1Outgoing

0Incoming

0Experiments

1Debates

Summary

Page for COQ9 Gene

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🧬 Gene Info

Gene Symbol	COQ9
Function	COQ9 Gene (Coenzyme Q Biosynthesis Factor 9) provides instructions for making the COQ9 protein, a mitochondrial lipid-binding protein essential for coenzyme Q (CoQ10) biosynthesis
Primary Expression	most tissues:
Molecular Weight	35 kDa
Amino Acids	312 aa
Exons	8 coding exons
UniProt ID	Q9UNM6
Ensembl ID	ENSG00000128604
GeneCards	COQ9
Human Protein Atlas	COQ9
Transcript length	~1.4 kb coding sequence
Protein length	312 amino acids
Molecular weight	~35 kDa
Brain	Throughout the CNS
Heart	High in cardiac muscle
Associated Diseases	neurodegeneration
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: COQ9 — AlphaFold Q9UNM6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

COQ9 Gene

gene · 647 words

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COQ9 Protein

protein · 884 words

→

Pathway Diagram

graph TD
    COQ9["COQ9"]
    neurodegeneration["neurodegeneration"]
    COQ9 -->|"implicated_in"| neurodegeneration
    style COQ9 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

Target	Relation	Type	Str
COQ7 complex stability	modulates	process	0.70

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

What molecular mechanisms cause iPLA2β deficiency to specifically damage mitocho

neurodegeneration | 2026-04-15 | 0 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The abstract shows that damaged mitochondrial inner membranes appear early in PL

closed · Rounds: 4 · Score: 0.95 · 2026-04-16

Related Research

Hypotheses and analyses mentioning COQ9 in their description or question text

No additional research found