Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COX7A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | COX7A2 |
| Full Name | Cytochrome c Oxidase Subunit VIIa (Liver) |
| Aliases | Page for COX7A2 |
| Chromosome | 6p21.3 |
| Function | is a small hydrophobic protein (approximately 61 amino acids) located in the intermembrane space arm of complex IV. |
| Primary Expression | many tissues, with the highest levels in energy-demanding tissues including heart, liver, and brain |
| Amino Acids | 61 aa |
| Exons | 2 |
| UniProt ID | P14406 |
| NCBI Gene ID | 9167 |
| Ensembl ID | ENSG00000180590 |
| OMIM | 603501 |
| GeneCards | COX7A2 |
| Human Protein Atlas | COX7A2 |
| Mitochondrial-encoded | COX1, COX2, COX3 (core catalytic subunits) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
COX7A2["COX7A2"]
neurodegeneration["neurodegeneration"]
COX7A2 -->|"implicated_in"| neurodegeneration
style COX7A2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COX7A2 in their description or question text
No additional research found