Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CPA6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CPA6 |
| Full Name | Carboxypeptidase A6 |
| Aliases | Page for CPA6 |
| Protein Type | Protease |
| Function | Carboxypeptidase A6 (CPA6) is a zinc-dependent metalloprotease belonging to the M14 family of metallocarboxypeptidases. |
| Primary Expression | the brain, particularly in the cerebellum, olfactory bulb, and specific neuronal populations |
| UniProt ID | [Q8N4T0](https://www.uniprot.org/uniprot/Q8N4T0) |
| Ensembl ID | ENSG00000156970 |
| GeneCards | CPA6 |
| Human Protein Atlas | CPA6 |
| Cerebellum | High expression in Purkinje cells and granule cell layers |
| Olfactory bulb | Involved in olfactory processing and neurogenesis |
| CPA1-5 | Other carboxypeptidase family members |
| CPE | Carboxypeptidase E - neuropeptide processing |
| EPM1 | Cystatin B - progressive myoclonus epilepsy |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CPA6["CPA6"]
neurodegeneration["neurodegeneration"]
CPA6 -->|"implicated_in"| neurodegeneration
style CPA6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CPA6 in their description or question text
No additional research found