gene

CPLX4

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CPLX4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Complexin 4 gene in neurodegeneration

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🧬 Gene Info

Gene Symbol	CPLX4
Aliases	Complexin-4
Chromosome	11q13.2
Function	CPLX4 encodes complexin 4, a neuronal protein involved in regulating synaptic vesicle fusion.
Primary Expression	various brain regions, with particularly high expression in retina and sensory neurons
Molecular Weight	34 kDa
Amino Acids	312 aa
Exons	5
UniProt ID	Q8WXD5
NCBI Gene ID	285315
Ensembl ID	ENSG00000177054
GeneCards	CPLX4
Human Protein Atlas	CPLX4
Associated Diseases	Autism spectrum disorder, synaptic transmission disorders, neurodegenerative diseases
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CPLX4 — AlphaFold Q8WXD5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CPLX4 Gene

gene · 578 words

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CPLX4 Protein

protein · 956 words

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Pathway Diagram

graph TD
    CPLX4["CPLX4"]
    neurodegeneration["neurodegeneration"]
    CPLX4 -->|"implicated_in"| neurodegeneration
    style CPLX4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CPLX4 in their description or question text

No additional research found