CRY1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCRY1
Namecryptochrome circadian regulator 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gen

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