CRYAB

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCRYAB
Namecrystallin alpha B
Typeprotein-coding
Sourcemygene

Summary

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggre

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