CYLD

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCYLD
NameCYLD lysine 63 deubiquitinase
Typeprotein-coding
Sourcemygene

Summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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