Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CYSTATINC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CYSTATINC |
| Full Name | Cystatin C (CST3) |
| Chromosome | 20 |
| Protein Type | Protein |
| Function | is a member of the type 2 cystatin family of cysteine protease inhibitors[@abrahamson1994]. |
| UniProt ID | Search UniProt |
| GeneCards | CYSTATINC |
| Human Protein Atlas | CYSTATINC |
| Cathepsin B, L, S | primary protease targets of cystatin C |
| Cystatin A, B, F | related cysteine protease inhibitors |
| Amyloid-beta | protein influenced by cystatin C-regulated proteolysis |
| Hereditary cerebral amyloid angiopathy | CST3 mutation-associated disease |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CYSTATINC["CYSTATINC"]
neurodegeneration["neurodegeneration"]
CYSTATINC -->|"implicated_in"| neurodegeneration
style CYSTATINC fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CYSTATINC in their description or question text
No additional research found