Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DAGLAPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
DAGLA is a large type I transmembrane protein consisting of 1048 amino acids with a molecular weight of approximately 120 kDa[@bisogno2003].
| Gene Symbol | DAGLAPROTEIN |
| Function | is a large type I transmembrane protein consisting of 1048 amino acids with a molecular weight of approximately 120 kDa[@bisogno2003]. |
| Subcellular Localization | ### Structural Insights |
| Molecular Weight | 120 kDa |
| Amino Acids | 1048 aa |
| GeneCards | DAGLAPROTEIN |
| Human Protein Atlas | DAGLAPROTEIN |
| Regulatory Mechanism | Effect on DAGLA |
| Calcium influx | Activation |
| Protein kinase A | Phosphorylation/inhibition |
| Protein kinase C | Phosphorylation/activation |
| Gq protein coupling | Activation |
| pH changes | pH-dependent activity |
| Compound | Target |
| DO34 | DAGLA activator |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
DAGLAPROTEIN["DAGLAPROTEIN"]
neurodegeneration["neurodegeneration"]
DAGLAPROTEIN -->|"implicated_in"| neurodegeneration
style DAGLAPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||