protein

DAGLBPROTEIN

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about DAGLBPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The DAGLB gene is located on chromosome 7p13 in humans and encodes a protein of approximately 90-100 kDa. The gene contains multiple exons and produces alternatively spliced variants [8].

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🔬 Protein Info

Gene Symbol	DAGLBPROTEIN
Full Name	Diacylglycerol Lipase Beta (DAGLβ)
Chromosome	7p13
Protein Type	Protein
Function	encodes a protein of approximately 90-100 kDa.
Primary Expression	peripheral tissues including the liver, kidney, and immune cells, it is also expressed in glial cells and certain neuronal populations where it plays
Subcellular Localization	- Serine hydrolase catalytic domain: Contains the active site serine - **Lip
Molecular Weight	100 kDa
UniProt ID	Search UniProt
GeneCards	DAGLBPROTEIN
Human Protein Atlas	DAGLBPROTEIN
Selectivity	Prefers DAG species containing arachidonic acid at the sn-1 position
Substrate specificity	Acts on various DAG species, with preference for 2-AG precursors
Cellular location	Active in cytosol and associated with endoplasmic reticulum membranes [6]
Molecular weight	~100 kDa
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: DAGLBPROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Diacylglycerol Lipase Beta (DAGLβ)

protein · 1210 words

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Pathway Diagram

graph TD
    DAGLBPROTEIN["DAGLBPROTEIN"]
    neurodegeneration["neurodegeneration"]
    DAGLBPROTEIN -->|"implicated_in"| neurodegeneration
    style DAGLBPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

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Related Papers (0)

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Related Research

Hypotheses and analyses mentioning DAGLBPROTEIN in their description or question text

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