gene

DCLRE1C

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about DCLRE1C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

DCLRE1C Gene

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🧬 Gene Info

Gene Symbol	DCLRE1C
Full Name	DNA Cross-Link Repair 1C (Artemis)
Chromosome	10p13
Function	The DCLRE1C gene encodes DNA Cross-Link Repair 1C (Artemis), involved in DNA repair and genomic stability
UniProt ID	DCLRE1C
NCBI Gene ID	64421
Ensembl ID	ENSG00000152457
OMIM	605988
GeneCards	DCLRE1C
Human Protein Atlas	DCLRE1C
DNA repair	Critical for maintaining genomic integrity
Cell cycle regulation	Coordinates DNA repair with cell cycle progression
[Apoptosis](/entities/apoptosis)	Modulates apoptotic response to DNA damage
Neuronal survival	Essential for long-term neuronal survival
L475P	functional studies
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DCLRE1C Gene

gene · 652 words

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Pathway Diagram

graph TD
    DCLRE1C["DCLRE1C"]
    neurodegeneration["neurodegeneration"]
    DCLRE1C -->|"implicated_in"| neurodegeneration
    style DCLRE1C fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DCLRE1C in their description or question text

No additional research found