DDIT3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolDDIT3
NameDNA damage inducible transcript 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromoso

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This is an externally resolved entity

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