PARK7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPARK7
NameParkinsonism associated deglycase
Typeprotein-coding
Sourcemygene

Summary

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provide

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