DLG3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolDLG3
Namediscs large MAGUK scaffold protein 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq

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