gene

DNAJB5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about DNAJB5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	DNAJB5
Full Name	DnaJ Heat Shock Protein Family (Hsp40) Member B5
Chromosome	9p13.3
Protein Type	Chaperone
Function	is a member of the DnaJ/Hsp40 family of molecular chaperones.
Amino Acids	70 aa
UniProt ID	O75164
NCBI Gene ID	25822
Ensembl ID	ENSG00000135919
OMIM	608591
GeneCards	DNAJB5
Human Protein Atlas	DNAJB5
J-Domain (1-70 aa)	The defining feature of DNAJ proteins, containing the conserved HPD motif
Gly/Phe-Rich Region (70-150 aa)	Flexible linker region
Proteasomal Degradation	Targets ubiquitinated misfolded proteins for degradation
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DNAJB5 — AlphaFold O75164 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DNAJB5 (DnaJ Heat Shock Protein Family Member B5)

gene · 2425 words

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Pathway Diagram

graph TD
    DNAJB5["DNAJB5"]
    neurodegeneration["neurodegeneration"]
    DNAJB5 -->|"implicated_in"| neurodegeneration
    style DNAJB5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DNAJB5 in their description or question text

No additional research found