protein

DNAJB8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNAJB8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Incoming

0Experiments

0Debates

Summary

Page for DNAJB8 Protein

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🔬 Protein Info

Gene Symbol	DNAJB8
Full Name	DnaJ Heat Shock Protein Family (Hsp40) Member B8
Chromosome	3p21.31
Protein Type	Chaperone
Function	DNAJB8 is a J-domain containing co-chaperone:
Primary Expression	stem cells and certain somatic tissues, including the brain, where it plays a role in protein quality control and may protect against age-related prot
Molecular Weight	35 kDa
UniProt ID	Q8N5M4
NCBI Gene ID	165727
Ensembl ID	ENSG00000179421
OMIM	—
GeneCards	DNAJB8
Human Protein Atlas	DNAJB8
Encoded Protein	DNAJB8 protein
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DNAJB8 — AlphaFold Q8N5M4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    DNAJB8["DNAJB8"]
    neurodegeneration["neurodegeneration"]
    DNAJB8 -->|"implicated_in"| neurodegeneration
    style DNAJB8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

DNAJB8

Understanding Entity Pages

Summary

Wiki Pages (7)

DNAJB8 Gene

Chaperone-Mediated Proteostasis Disease Comparison

DNAJB5 (DnaJ Heat Shock Protein Family Member B5)

DNAJB2 — DNAJ Heat Shock Protein Family Member B2

DNAJB8 Protein

Proteins

Genes