Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about DNAJC11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive page on DNAJC11 protein - mitochondrial co-chaperone involved in protein quality control and neurodegenerative diseases
| Gene Symbol | DNAJC11 |
| Full Name | DNAJ Heat Shock Protein Family Member C11 |
| Aliases | Comprehensive page on DNAJC11 protein |
| Chromosome | 1p36.22 |
| Protein Type | Chaperone |
| Function | DNAJC11 encodes a DnaJ/Hsp40 co-chaperone protein localized to the mitochondrial matrix. |
| Subcellular Localization | the mitochondrial matrix. It functions as a co-chaperone that assists Hsp70 in protein folding and mitochondrial protein |
| Molecular Weight | 38.5 kDa |
| Amino Acids | 341 aa |
| UniProt ID | [Q9NVH1](https://www.uniprot.org/uniprot/Q9NVH1) |
| Ensembl ID | ENSG00000054148 |
| OMIM | 617761 |
| GeneCards | DNAJC11 |
| Human Protein Atlas | DNAJC11 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
DNAJC11["DNAJC11"]
neurodegeneration["neurodegeneration"]
DNAJC11 -->|"implicated_in"| neurodegeneration
style DNAJC11 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity