gene

DNAJC28

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about DNAJC28: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for DNAJC28 Gene

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🧬 Gene Info

Gene Symbol	DnaJ Heat Shock Protein Family Member C28
Chromosome	21q22.11
Protein Type	Chaperone
Function	These proteins function as co-chaperones, working in concert with Hsp70 proteins to regulate protein folding, refolding, assembly, and degradation[@kampinga2019][@hasson2015].
Primary Expression	Testis-specific
Subcellular Localization	Cytoplasm (predicted)
Molecular Weight	41 kDa
Amino Acids	70 aa
Gene Type	Protein coding
UniProt ID	Q9H0Z2
NCBI Gene ID	254268
Ensembl ID	ENSG00000178104
OMIM	619044
J-domain	The defining characteristic of DNAJ proteins, approximately 70 amino acids in length
Gly/Phe-rich region	Likely present in the N-terminal region
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DNAJC28 — AlphaFold Q9H0Z2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DNAJC28 Gene

gene · 1319 words

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Pathway Diagram

graph TD
    DNAJC28["DNAJC28"]
    neurodegeneration["neurodegeneration"]
    DNAJC28 -->|"implicated_in"| neurodegeneration
    style DNAJC28 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DNAJC28 in their description or question text

No additional research found