gene

DNAJC8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNAJC8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for DNAJC8 Gene

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🧬 Gene Info

Gene Symbol	DNAJC8
Full Name	DnaJ/Hsp40 Co-Chaperone C8
Aliases	DNAJC8, SPFH2, Hsp40
Chromosome	1
Protein Type	Chaperone
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	neuronal tissues with highest expression in: - Cerebral cortex (pyramidal neurons) - Hippocampus (CA1-CA3 regions) - Cerebellum (Purkinje cells) - Spi
Molecular Weight	31.3 kDa
Amino Acids	335 aa
Exons	9
GeneCards	DNAJC8
Human Protein Atlas	DNAJC8
Location	1q21.2
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    DNAJC8["DNAJC8"]
    neurodegeneration["neurodegeneration"]
    DNAJC8 -->|"implicated_in"| neurodegeneration
    style DNAJC8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity