DOCK3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolDOCK3
Namededicator of cytokinesis 3
Typeprotein-coding
Sourcemygene

Summary

This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE

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