gene

DRAM2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about DRAM2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

DRAM2 Gene

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🧬 Gene Info

Gene Symbol	DRAM2
Protein Type	Gene
Function	DNA Damage Regulated Autophagy Modulator 2 (DRAM2) is a lysosomal protein that plays a critical role in autophagy and cell survival under stress conditions.
Primary Expression	neurons and glial cells, with elevated expression under cellular stress conditions
Subcellular Localization	- Lysosomal membranes
GeneCards	DRAM2
Human Protein Atlas	DRAM2
Brain	Moderate expression in cortex, hippocampus, and cerebellum
Heart	High expression
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DRAM2 Gene

gene · 776 words

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Pathway Diagram

graph TD
    DRAM2["DRAM2"]
    neurodegeneration["neurodegeneration"]
    DRAM2 -->|"implicated_in"| neurodegeneration
    style DRAM2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DRAM2 in their description or question text

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