DRD2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolDRD2
Namedopamine receptor D2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008].

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