concept

DUBS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DUBS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections
0Hypotheses
0Analyses
2Outgoing
3Incoming
0Experiments

No summary available yet. View on Wiki →

💡 Concept Info
NameDUBS
Related DiseasesROS, OXIDATIVE_STRESS
Related PathwaysUBIQUITIN_SIGNALING, OXIDATIVE_STRESS_RESPONSE, REDOX_REGULATION

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

proteasome-ubiquitin-system-dysfunction-parkinsons

general · 3977 words

Necroptotic Neurons

cell · 3674 words

ubiquitin-proteasome-dysfunction-neurodegeneration

mechanism · 3548 words

UCHL1 (PARK5) Pathway in Parkinson's Disease

mechanism · 3394 words

Pathway Diagram

graph TD
    DUBS["DUBS"]
    DUBS -->|"regulates"| Ubiquitin_Signaling["Ubiquitin Signaling"]
    DUBS -->|"cleaves"| UBIQUITIN["UBIQUITIN"]
    DUBS -->|"inhibits"| UBIQUITIN_CONJUGASES["UBIQUITIN CONJUGASES"]
    DUBS -->|"modulates"| Protein_Activity["Protein Activity"]
    DUBS -->|"regulates"| Protein_Stability["Protein Stability"]
    DUBS -->|"regulates"| Protein_Localization["Protein Localization"]
    DUBS -->|"regulates"| Ubiquitination["Ubiquitination"]
    DUBS -->|"regulates"| UBIQUITIN_SIGNALING["UBIQUITIN_SIGNALING"]
    Reactive_Oxygen_Species["Reactive Oxygen Species"] -->|"modulates"| DUBS
    Protein_Protein_Interaction["Protein-Protein Interaction"] -->|"regulates"| DUBS
    Posttranslational_Modification["Posttranslational Modification"] -->|"regulates"| DUBS
    ROS["ROS"] -->|"regulates"| DUBS
    OXIDATIVE_STRESS["OXIDATIVE_STRESS"] -->|"regulates"| DUBS
    REDOX_REGULATION["REDOX_REGULATION"] -->|"regulates"| DUBS

Outgoing (2)

TargetRelationTypeStr
UBIQUITIN_SIGNALINGregulatespathway0.72
OXIDATIVE_STRESS_RESPONSEparticipates_inpathway0.64

Incoming (3)

SourceRelationTypeStr
ROSregulatesphenotype0.64
OXIDATIVE_STRESSregulatesphenotype0.64
REDOX_REGULATIONregulatespathway0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found