gene

DUSP11

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DUSP11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Page for DUSP11 Gene

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🧬 Gene Info

Gene Symbol	DUSP11
Chromosome	2p13.2
Protein Family	Dual-specificity phosphatase (DUSP) family
Protein Type	Phosphatase
Function	encodes an RNA phosphatase that specifically dephosphorylates the Ser5 CTD (C-terminal domain) of RNA polymerase II.
Primary Expression	various brain regions including cortex, hippocampus, cerebellum, and basal ganglia
Subcellular Localization	**: Primarily nuclear, with some cytoplasmic localization
Molecular Weight	82 kDa
Amino Acids	736 aa
UniProt ID	Q9Y3T5
NCBI Gene ID	5685
Ensembl ID	ENSG00000141428
OMIM	607621
GeneCards	DUSP11
Human Protein Atlas	DUSP11
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DUSP11 — AlphaFold Q9Y3T5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

DUSP11 Gene

gene · 1300 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    DUSP11["DUSP11"]
    neurodegeneration["neurodegeneration"]
    DUSP11 -->|"implicated_in"| neurodegeneration
    style DUSP11 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found