Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DUSP14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DUSP14 |
| Protein Type | Phosphatase |
| Function | is a member of the dual-specificity phosphatase (DUSP) family that dephosphorylates both tyrosine and threonine residues on MAP kinases. |
| Primary Expression | substantia nigra pars compacta |
| Pathways | MAPK |
| Ensembl ID | ENSG00000156345 |
| GeneCards | DUSP14 |
| Human Protein Atlas | DUSP14 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
DUSP14["DUSP14"]
neurodegeneration["neurodegeneration"]
DUSP14 -->|"implicated_in"| neurodegeneration
style DUSP14 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DUSP14 in their description or question text
No additional research found