gene

DYNC2H1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DYNC2H1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

DYNC2H1 — Dynein Cytoplasmic 2 Heavy Chain 1

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🧬 Gene Info

Gene Symbol	DYNC2H1
Full Name	Dynein Cytoplasmic 2 Heavy Chain 1
Aliases	DYH1, HL12, DYHC2, DNCH2, DHC2
Chromosome	11q22.3
Gene Type	Protein-coding
UniProt ID	Q8IVD4
NCBI Gene ID	1771
Ensembl ID	ENSG00000130938
GeneCards	DYNC2H1
Human Protein Atlas	DYNC2H1
Interactor	Function
DYNC2I1	Intermediate chain - cargo binding
DYNC2I2	Alternative intermediate chain
DYNC2LI1	Light intermediate chain
DYNC2LI2	Alternative light intermediate chain
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DYNC2H1 — AlphaFold Q8IVD4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    DYNC2H1["DYNC2H1"]
    neurodegeneration["neurodegeneration"]
    DYNC2H1 -->|"implicated_in"| neurodegeneration
    style DYNC2H1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity