Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DYNLL2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | DYNLL2 |
| Full Name | Dynein Cytoplasmic 1 Light Chain 2 |
| Chromosome | 17q21.2 |
| Function | DYNLL2 is a dynein light chain with high similarity to DYNLL1. |
| Primary Expression | brain and peripheral tissues |
| UniProt ID | [Q96E39](https://www.uniprot.org/uniprotkb/Q96E39/entry) |
| GeneCards | DYNLL2 |
| Human Protein Atlas | DYNLL2 |
| DYNLL1 | Paralogous light chain with overlapping but distinct functions |
| DCTN1 | Dynactin subunit; mutations affect DYNLL2-mediated processes |
| Cytoplasmic Dynein-1 | Parent motor complex |
| Microtubule Transport System | Functional context |
| Associated Diseases | Motor neuron disease (potential) |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
DYNLL2["DYNLL2"]
neurodegeneration["neurodegeneration"]
DYNLL2 -->|"implicated_in"| neurodegeneration
style DYNLL2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||