ARHGEF11

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolARHGEF11
NameRho guanine nucleotide exchange factor 11
Typeprotein-coding
Sourcemygene

Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of mem

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