gene

EFNA4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EFNA4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

EFNA4 (Ephrin A4) - GPI-anchored ligand for EPHA receptors, critical for synaptic plasticity, neural development, and implicated in neurodegenerative diseases

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	EFNA4
Full Name	Ephrin A4
Chromosome	1q21.3
Function	is a member of the ephrin family of cell surface proteins that function as ligands for EPHA receptor tyrosine kinases.
Primary Expression	Brain (cortex, hippocampus), lung, liver, kidney
Amino Acids	233 aa
UniProt ID	[P52802](https://www.uniprot.org/uniprotkb/P52802/entry)
Ensembl ID	ENSG00000126247
GeneCards	EFNA4
Human Protein Atlas	EFNA4
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

EFNA4 Gene

gene · 2878 words

→

Pathway Diagram

graph TD
    EFNA4["EFNA4"]
    neurodegeneration["neurodegeneration"]
    EFNA4 -->|"implicated_in"| neurodegeneration
    style EFNA4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EFNA4 in their description or question text

No additional research found