gene

EHMT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EHMT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

EHMT1 — euchromatic histone lysine methyltransferase 1

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🧬 Gene Info

Gene Symbol	EHMT1
Full Name	G9a (Gene 9 Protein)
Aliases	euchromatic histone lysine methyltransferase 1
Protein Family	Su(var)3-9 Family
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	Nucleus, Chromatin
Molecular Weight	140 kDa
UniProt ID	Q9GZF2
GeneCards	EHMT1
Human Protein Atlas	EHMT1
Huntington's Disease	Involved in transcriptional dysregulation caused by mutant huntingtin protein
Epigenetic drugs	Small molecules that modulate histone methyltransferase activity
Gene therapy	Viral vectors delivering functional copies of EHMT1
Protein-protein interaction inhibitors	Disrupt aberrant interactions
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: EHMT1 — AlphaFold Q9GZF2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

EHMT1 — euchromatic histone lysine methyltransferase 1

gene · 601 words

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G9a/GLP Histone H3K9 Methyltransferase (EHMT1)

protein · 535 words

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Pathway Diagram

graph TD
    EHMT1["EHMT1"]
    neurodegeneration["neurodegeneration"]
    EHMT1 -->|"implicated_in"| neurodegeneration
    style EHMT1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EHMT1 in their description or question text

No additional research found