protein

EIF2B4

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about EIF2B4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for eIF2B4 Protein

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🔬 Protein Info

Gene Symbol	EIF2B4
Function	EIF2B4 encodes the delta subunit of eukaryotic translation initiation factor 2B (eIF2B), the guanine nucleotide exchange factor (GEF) that recycles eIF2-GDP to eIF2-GTP.
Primary Expression	oligodendrocytes, astrocytes, and neurons
Molecular Weight	58 kDa
UniProt ID	EIF2B4
Ensembl ID	ENSG00000109771
GeneCards	EIF2B4
Human Protein Atlas	EIF2B4
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: EIF2B4 — AlphaFold EIF2B4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

EIF2B4

gene · 578 words

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Pathway Diagram

graph TD
    EIF2B4["EIF2B4"]
    neurodegeneration["neurodegeneration"]
    EIF2B4 -->|"implicated_in"| neurodegeneration
    style EIF2B4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

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