Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ELOVL4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ELOVL4 |
| Full Name | ELOVL Fatty Acid Elongase 4 |
| Chromosome | 6q14.1 |
| Protein Type | Enzyme |
| Function | ELOVL4 encodes a member of the ELOVL (elongation of very long chain fatty acids) family of proteins, which catalyze the initial condensation step of fatty acid elongation. |
| Primary Expression | neurons, photoreceptors, and oligodendrocytes |
| Molecular Weight | 34.9 kDa |
| Amino Acids | 314 aa |
| UniProt ID | [Q9GZR7](https://www.uniprot.org/uniprot/Q9GZR7) |
| Ensembl ID | ENSG00000153902 |
| OMIM | 614512 |
| GeneCards | ELOVL4 |
| Human Protein Atlas | ELOVL4 |
| Fatty acid supplementation | Providing VLC-PUFAs bypasses the biosynthetic block |
| Gene therapy | AAV-mediated ELOVL4 delivery to retina and brain |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ELOVL4["ELOVL4"]
neurodegeneration["neurodegeneration"]
ELOVL4 -->|"implicated_in"| neurodegeneration
style ELOVL4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ELOVL4 in their description or question text
No additional research found