gene

EPM2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EPM2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
0Hypotheses
0Analyses
1Outgoing
1Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolEPM2A
Full NameEPM2A Glial Protein (Laforin)
AliasesLaforin
Chromosome6q24
Protein TypePhosphatase
Functionis a critical gene located on chromosome 6q24 that encodes a unique dual-specificity phosphatase essential for glycogen metabolism.
Molecular Weight37 kDa
Amino Acids331 aa
UniProt ID[Q9U6X3](https://www.uniprot.org/uniprot/Q9U6X3)
Ensembl IDENSG00000129680
GeneCardsEPM2A
Human Protein AtlasEPM2A
Associated Diseasesneurodegeneration
KG Connections2 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (10)

Knowledge base pages for this entity

Canonical Page

EPM2A Gene

gene · 1913 words

Myoclonus and Cortical Hyperexcitability in Corticobasal Syndrome

mechanism · 6138 words

Progressive Myoclonic Epilepsies (PME)

disease · 2103 words

Lafora Disease

disease · 1649 words

Dentate Gyrus Granule Cells in Lafora Disease

cell · 1084 words

Progressive Myoclonus Epilepsy

disease · 958 words

Pathway Diagram

graph TD
    EPM2A["EPM2A"]
    neurodegeneration["neurodegeneration"]
    EPM2A -->|"implicated_in"| neurodegeneration
    style EPM2A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

TargetRelationTypeStr
ds-83b31ef18d49provides_data_fordataset1.00

Incoming (1)

SourceRelationTypeStr
ds-83b31ef18d49data_indataset1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found