Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ERCC6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Gene Symbol | ERCC6 |
| Full Name | Excision Repair Cross-Complementation Group 6 |
| Function | The ERCC6/CSB protein is a key regulator of transcription-coupled DNA repair: |
| Primary Expression | glial cells |
| Ensembl ID | ENSG00000225830 |
| GeneCards | ERCC6 |
| Human Protein Atlas | ERCC6 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ERCC6["ERCC6"]
neurodegeneration["neurodegeneration"]
ERCC6 -->|"implicated_in"| neurodegeneration
style ERCC6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ERCC6 in their description or question text
No additional research found