Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FAM126A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | FAM126A |
| Chromosome | 7p15.3 |
| Function | The FAM126A protein is primarily expressed in oligodendrocytes and Schwann cells, the myelin-producing cells of the CNS and PNS respectively. |
| Primary Expression | Brain, Spinal Cord, Peripheral Nerves |
| UniProt ID | Q8IZJ3 |
| NCBI Gene ID | 55278 |
| Ensembl ID | ENSG00000146243 |
| OMIM | 613026 |
| GeneCards | FAM126A |
| Human Protein Atlas | FAM126A |
| Myelin biogenesis | Regulating the synthesis and assembly of myelin lipids and proteins |
| Oligodendrocyte differentiation | Supporting the maturation of oligodendrocyte precursor cells |
| Schwann cell function | Maintaining peripheral nerve myelination |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
FAM126A["FAM126A"]
neurodegeneration["neurodegeneration"]
FAM126A -->|"implicated_in"| neurodegeneration
style FAM126A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FAM126A in their description or question text
No additional research found