Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FANCF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | FANCF |
| Full Name | Fanconi Anemia Group F |
| Chromosome | 11p15 |
| Protein Type | Scaffold Protein |
| Function | These interactions are essential for the stability and function of the complex[@liu2007]. |
| Molecular Weight | 42 kDa |
| Amino Acids | 380 aa |
| UniProt ID | [Q9NPI8](https://www.uniprot.org/uniprot/Q9NPI8) |
| Ensembl ID | ENSG00000163930 |
| GeneCards | FANCF |
| Human Protein Atlas | FANCF |
| FANCA | Largest subunit, forms the core scaffold |
| FANCB | Catalytic component |
| FANCC | Stabilizes the complex |
| FANCD2 | Ubiquitination substrate (forms ID complex with FANCI) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
FANCF["FANCF"]
neurodegeneration["neurodegeneration"]
FANCF -->|"implicated_in"| neurodegeneration
style FANCF fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FANCF in their description or question text
No additional research found