FASLG

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolFASLG
NameFas ligand
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus eryt

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