gene

FCGR1A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FCGR1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Page for FCGR1A gene

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🧬 Gene Info

Gene Symbol	FCGR1A
Full Name	Fc Gamma Receptor IA
Protein Type	Receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	45 kDa
Pathways	PI3K, MAPK, NF-κB, MAPK pathway
Ensembl ID	ENSG00000110324
GeneCards	FCGR1A
Human Protein Atlas	FCGR1A
Extracellular domain	Three Ig-like domains (α1, α2, α3)
Transmembrane domain	Single pass helix
Intracellular domain	ITAM motif for signal transduction
Monocytes/Macrophages	High expression
Dendritic Cells	Moderate expression
Neutrophils	Low/inducible expression
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

FCGR1A - Fc Gamma Receptor IA

gene · 1004 words

→

FCGR1A Protein - Fc Gamma Receptor IA

protein · 910 words

→

Pathway Diagram

graph TD
    FCGR1A["FCGR1A"]
    neurodegeneration["neurodegeneration"]
    FCGR1A -->|"implicated_in"| neurodegeneration
    style FCGR1A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FCGR1A in their description or question text

No additional research found