gene

FCGR2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FCGR2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Fc gamma receptor IIa (FCGR2A)

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🧬 Gene Info

Gene Symbol	FCGR2A
Chromosome	1q23.3
Protein Type	Receptor
Function	FCGR2A encodes a transmembrane glycoprotein receptor that binds the Fc region of IgG antibodies.
GeneCards	FCGR2A
Human Protein Atlas	FCGR2A
Variant	rsID
R131H	rs3890115
Q27W	rs10800309
A87S	rs3916879
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    FCGR2A["FCGR2A"]
    IGG(["IGG"])
    AKT(["AKT"])
    Monoclonal_Antibodies{"Monoclonal Antibodies"}
    neurodegeneration["neurodegeneration"]

    IGG -->|"binds"| FCGR2A
    FCGR2A -->|"activates"| AKT
    Monoclonal_Antibodies -->|"interacts with"| FCGR2A
    FCGR2A -->|"implicated in"| neurodegeneration

    style FCGR2A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style IGG fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style AKT fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style Monoclonal_Antibodies fill:#1a3a3a,stroke:#4dd0e1,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity