gene

FGF16

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FGF16: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Fibroblast Growth Factor 16 - a member of the FGF family involved in neural development and cellular proliferation

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🧬 Gene Info

Gene Symbol	FGF16
Full Name	Fibroblast Growth Factor 16
Chromosome	Xq21.3
Function	is a member of the fibroblast growth factor family that plays important roles in development, tissue maintenance, and cellular function.
Primary Expression	Brain, heart, limb buds, regenerating tissues
Molecular Weight	23 kDa
Amino Acids	207 aa
UniProt ID	[O43558](https://www.uniprot.org/uniprot/O43558)
Ensembl ID	ENSG00000196437
OMIM	300822
GeneCards	FGF16
Human Protein Atlas	FGF16
Heparin-binding domain	Facilitates interaction with FGFRs and heparan sulfate proteoglycans
RAS/MAPK pathway	Cell proliferation, differentiation
PI3K/AKT pathway	Cell survival, metabolism
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    FGF16["FGF16"]
    neurodegeneration["neurodegeneration"]
    FGF16 -->|"implicated_in"| neurodegeneration
    style FGF16 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

FGF16

Understanding Entity Pages

Summary

Wiki Pages (7)

FGF16 Gene

FGF10 — Fibroblast Growth Factor 10

FGF Signaling Pathway in Neurodegeneration

FGF Signaling in Parkinson's Disease

Fibroblast Growth Factor Signaling in Neurodegeneration

FGF13-MTCH2 Neuroprotection in Parkinson's Disease